The ISTH has published new guidelines on Thrombotic Thrombocytopenic Purpura.
TTP is a rare, life-threatening thrombotic microangiopathy or blood disorder. In TTP, blood clots form in small blood vessels throughout the body and can limit or block the flow of oxygen-rich blood to the body’s organs, such as the brain, kidneys and heart. This can result in serious health problems. The reported incidence of TTP is two to six cases per million per year and a mortality of 10-20 percent upon proper treatment.
The challenge is that there are a number of conditions that have clinical and laboratory presenting features similar to those of TTP. A number of new therapeutic agents have been developed, requiring detailed guidance to properly manage treatment. The ISTH TTP Guidelines provide important recommendations, which will improve the management of patients with TTP.
Check out the guidelines over here